This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Spindle assembly checkpoint (SAC) inhibitors ...

One specific system under investigation is the ubiquitin-proteasome system (UPS). This system plays a central role in most cellular processes. New data suggest that UPS plays a role beyond its known ...