Uveal melanoma is a type of cancer that develops in the middle layer of your eye called the uvea. It can cause symptoms like blurry vision, floaters, or loss of vision. Melanoma is a type of ...

Uveal melanoma is the most common primary malignancy of the eye and frequently leads to metastatic death. Until the mid-20th Century, the only treatment for uveal melanoma was enucleation.

In contrast to many other cancer types, UM is often diagnosed based on clinical examinations without histological assessment. 6 Ophthalmologists and ophthalmic oncologists use various techniques ...

1Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, Pennsylvania.

The RP2-202 trial is a Phase 2/3 study assessing RP2 in combination with nivolumab versus nivolumab and ipilimumab in immune checkpoint inhibitor-naïve patients with metastatic uveal melanoma.

Tebentafusp is recommended, within its marketing authorisation, for treating HLA‑A*02:01-positive unresectable or metastatic uveal melanoma in adults. Tebentafusp is only recommended if the company ...

Tebentafusp (Kimmtrak, Immunocore) is indicated 'as monotherapy for the treatment of human leukocyte antigen (HLA)‑A*02:01-positive adult patients with unresectable or metastatic uveal melanoma'. The ...

A PET scan can help doctors spot cancer that has spread through the body. A doctor may request one during the melanoma diagnostic process if they suspect advanced melanoma cancer. A PET scan is an ...

The number stage of a melanoma tells you how thick it is and whether it has spread. It also tells you whether the top layer of the melanoma looks broken (ulcerated) when looked at under a microscope.

The Breslow thickness describes how deep a melanoma has grown into the layers of skin. Doctors need to know the depth of a melanoma to help stage it. The stage tells you the size of a cancer and if it ...

mRNA specialist BioNTech has chalked up an important win in its cancer pipeline, showing efficacy with its BNT111 vaccine candidate in a phase 2 trial in advanced melanoma. The study is looking at ...