V-161, a novel compound targeting the Na+ -V-ATPase enzyme in vancomycin-resistant Enterococcus faecium (VRE), significantly reduces bacterial growth and colonization.A recent study has ...

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肺动脉高压（PAH）是一种危害严重的心肺疾病，它的特点在于病情会逐渐加重，伴随着明显的症状，并且在病情持续发展下可能会致命。PAH的主要病理特征是肺动脉的结构发生改变，同时血液循环的动力学也出现异常。尽管在过去十年中，PAH的治疗取得了显著进展，但诊断延迟和治疗效果不理想仍然是实现最佳结果的主要障碍。PAH的发病机制复杂，涉及多种病理生理过程，其中炎症和代谢紊乱的作用逐渐受到关注。

Figure 2. Schematic diagram of the bacterial flagellum. The bacterial flagellum is composed of basal body rings, namely the C-ring, MS-ring, L-ring, and P-ring, and an axial structure consisting of ...

ATPase activity of the SMARCAL1 mutants was measured using the Kinase-Glo Luminescent Kinase Assay (Promega, Madison, Wisconsin, USA). The ATPase reaction was performed using 20 ng/μl of SMARCAL1 ...

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Cell cycle re-entry of senescent breast cancer cells after CDK4/6 inhibition (CDK4/6i) constitutes a major source of disease ...

Taking to the simplistic setting of the Museum of Modern Art, Tory Burch’s latest collection of statements and staples drew an iconic crowd. 1 day ago Synaesthesia Inspires Pharrell Williams For New ...

在自然界中，大多数细菌生长缓慢，营养限制是主要原因之一。细菌通常需要将环境中的大分子物质分解并吸收其营养成分，以维持自身生长。例如，在实验室微生物培养中，常用酶降解的酪蛋白（牛奶中的主要蛋白质成分）水解产物作为营养源，为细菌生长提供固定氮和氨基酸，因为完整的蛋白质通常太大，无法被细菌直接摄取 ...

Given that RNase E forms a complex (the RNA degradosome) with the ATPase RhlB and other proteins 6, might this ATPase moonlight as an RNA pyrophosphatase? Does the RNA pyrophosphatase have to be ...