Damage to the cell wall can lead to vacuole rupture and cell death. A conserved mechanism involving ATG8ylation, where ATG8 is relocated to the vacuole membrane, helps protect against this.

New York’s Gateway Development Commission (GDC) Board of Commissioners has today awarded the contract for the Manhattan Tunnel Project to Frontier-Kemper-Tutor-Perini JV and authorized the notice to ...

2015; Monel et al., 2017). Therefore, an investigation of the vacuole origin and properties will contribute to elucidating the mechanisms of the pathomorphological effects of vacuolization inducers.

During acute glucose restriction, activated AMPK was stabilized from degradation and interacted with Atg14p. This prompted Atg14p redistribution from ER exit sites onto liquid-ordered vacuole membrane ...