通过详细分析这两个分子的作用,本文将探讨cAMP和cGMP在勃起中的相对重要性。 cAMP是由三磷酸腺苷(ATP)通过酶腺苷酸环化酶(adenylyl cyclase)转化而来的环状核苷酸。它作为第二信使,参与多种生物学过程,包括细胞代谢、激素信号传导、基因表达和肌肉放松等。
Alcohol is one of the most widely used substances. Alcohol use accounts for 5.1% of the global disease burden, contributes substantially to societal and economic costs, and leads to approximately 3 ...
Amyotrophic lateral sclerosis (ALS) is a fatal disease, characterized by the degeneration of both upper and lower motor neurons. Despite decades of research, we still to date lack a cure or disease ...
Seven-transmembrane receptors (7TMRs), also known as G protein-couple receptors, are the largest class of transmembrane receptors and a common target for therapeutics. Initially thought to signal ...
它的靶点广泛,如 mTOR、JAK、β-amyloid、Adenylyl cyclase、IKKβ、DNA polymerase。Resveratrol 也是一种特异性的 SIRT1 活化剂。Resveratrol 是有效的孕烷 X 受体 (PXR) 抑制剂。Resveratrol 是一种 Nrf2 激活剂,在小鼠模型中可以改善衰老相关的进行性肾损伤。Resveratrol 作用于内皮细胞 ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Axon pruning is a unique process neurons ...