Recently identified 'specialized' or translesion synthesis (TLS) polymerases supplement the activities of the five 'canonical' polymerases to replicate or facilitate the repair of damaged DNA.

Mitochondrial DNA (mtDNA) replication is essential for mitochondrial function. This is carried out by a dedicated DNA polymerase gamma, with 5’–3’ polymerase and 3’–5’ proofreading/ exonuclease ...

Bakuchiol inhibited DNA replication and activated the checkpoint kinase CHK1 by targeting DNA polymerases. Isobavachalcone interfered with DNA double-strand break (DSB) repair by inhibiting the ...

Learning about your genetics and ancestry is easier than ever. All you need to do is choose from the many DNA ancestry tests available online, receive your kit and send back the required DNA samples.

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The Repair Shop viewers were blown away by the restoration of a historic rugby shirt ...

Comparison of that ancient DNA with modern human DNA showed that the two species had interbred and that people today still carry the genetic fingerprint of that intermixing. Since then ...

Figure 4 pUL13 phosphorylates H2AX to promote viral replication. The conserved herpesvirus Protein kinase pUL13 regulates DNA damage marker H2A histone family member X (H2AX), and pUL13-mediated H2AX ...

The original electronics tool kit: Designed for computer, smartphone, tablet, and gaming repair, backed by thousands of free instructions. Intentional selection: All the tools you need ...

While most types of DNA damage are repaired by the body’s natural DNA repair mechanisms, some forms of damage can evade these processes and persist for years, according to new research. This prolonged ...