Updated results from BP1001-A obesity and Type 2 diabetes testing from the second stage of pre-clinical testing are as follows: Previously, Bio-Path reported BP1001-A increased insulin sensitivity in ...

Conventional methods to implant myoblasts, precursors to muscle fiber, require prior scarring for the new cells to graft properly. By adding extracellular matrix (ECM) fluid into the implant ...

In contrast to the inhibitory activities of myostatin and TGF-β on myogenic differentiation, exposure of myoblasts to BMPs redirects their differentiation towards the osteoblast lineage while ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The bioenergetic requirements of muscle stem ...

have revealed that the change in the intracellular calcium dynamics causes not only cellular stress but also degradation of specific proteins in myoblasts before they form myotubes—the immature ...

This study provides valuable information on the single nucleus RNA sequencing transcriptome, pathways, and cell types in pig skeletal muscle in response to conjugated linoleic acid (CLA) ...

为解决成肌细胞分离难题，研究人员优化分离及分化培养方案，发现 DMEM 更利于分化，意义重大。 在肌肉的世界里，有一种神奇的细胞 —— 成肌细胞（Myoblasts），它就像是肌肉生长和修复的 “小工匠”。成肌细胞起源于肌肉干细胞（MuSCs）的增殖，在维持骨骼 ...

本研究中，研究人员通过对 DH 和 TC 两种鸡品种胚胎骨骼肌的单细胞转录组分析，发现藏鸡表现出更早的胚胎肌发生和较少的肌原纤维细胞（Myoblasts），而 Daheng 肉鸡则表现出更活跃的蛋白合成相关基因表达。通过对肌原纤维细胞和成纤维脂肪祖细胞（Fibro ...

Introduction: Respiratory sarcopenia, characterized by reduced respiratory muscle mass and strength, is underdiagnosed in older adults. This cross-sectional study aimed to investigate the association ...