A novel strategy using lipid nanoparticles to reprogram liver immunity shows promise in generating antitumor responses ...
Fibrosis occurs earliest in regions where injury is most severe. In normal liver, hepatic stellate cells (HSCs) are nonparenchymal, quiescent cells whose main functions is to store vitamin A and ...
Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States Alnylam ...
Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China ...
Figure 1: β-galactosidase expression in mouse liver following lentiviral transduction. We analysed liver toxicity in rodents by measuring the serum alanine aminotransferase (ALT) concentration, a ...
This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license. This work is licensed under a Creative Commons ...
Chronic hepatic disease damages the liver and the resulting wound-healing process might lead to liver fibrosis and subsequent cirrhosis development. Fibrosis is the excessive deposition of ...