Childhood or young adult onset patients usually with acromegaly can also have mutations in the AIP gene without a known family history of pituitary adenoma. DNA (Deoxyribose Nucleic Acid) is the ...

The red bar represent subjects who have acromegaly/gigantism and harbour the "Irish" AIP mutation. The blue bar represents patients with acromegaly but without the AIP mutation. These findings may ...

Mutations in the aryl hydrocarbon receptor interacting protein gene (AIP) are seen in a minority (15%) of FIPA families and half of homogeneous acromegaly families have AIP mutations. Most AIP ...