We have been exploring the potential of the neuromodulator, adenosine, to reduce excessive dopamine signaling that contributes to the development and persistence of psychostimulant abuse. Dopamine’s ...

Caffeine and other methylxanthines can block the effects of adenosine and should be avoided 24 hours prior to use for stress testing. Also, persantine is similar in mechanism of action ...

med.nyu.edu Thus, in the paper by Riksen and colleagues published in this issue the authors provide some of the first evidence that methotrexate treatment for RA leads to altered adenosine kinetics in ...

Objectives To compare fractional flow reserve (FFR) obtained during maximal hyperaemia by Intravenous (IV) ATP and adenosine. Methods 23 patients with 25 lesions underwent determination of FFR with ...

Background Methotrexate is the cornerstone DMARD in the treatment of rheumatoid arthritis. The exact mechanism of action is elusive, but it may be related to increase in adenosine levels. Methotrexate ...