The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

Department of Chemistry, Faculty of Science, The Hashemite University, Zarqa 13133, Jordan Department of Physics, Virginia Tech, Blacksburg, Virginia 24061, United States Center for Soft Matter and ...

Nephrotoxicity, the major complication of long-term therapy with amphotericin B, is attributed to drug-induced renal vasoconstriction plus a direct toxic action on renal tubules. Hypokalemia and ...

Center for Translational Biomedical Research, University of North Carolina at Greensboro, Kannapolis, North Carolina 28081, United States Department of Chemistry & Biochemistry, University of North ...

This study provides useful insights into the ways in which germinal center B cell metabolism, particularly lipid metabolism, affects cellular responses. The authors use sophisticated mouse models to ...

A liposomal irinotecan formulation has been shown to have multimechanistic activity: Cytotoxic activity against tumor cells with demonstrated efficacy in a wide range of animal xenograft models.

The studies also show the potential of HighField’s unique lipid-based drug development platforms for designing antibody conjugated tLNPs for gene editing of T cells, B cells, NK cells ...

Pegylated liposomal doxorubicin (Doxil ®) is the only ... Combinations of Doxil with other lipid-based drug formulations show promise based on preclinical studies. With HGSC being primarily ...

(NYSE American: MTNB) announces that negotiations under the previously disclosed non-binding term sheet regarding global rights to MAT2203, its oral formulation of amphotericin B, have been ...

including lipid synthesis and liposomal formulation. Lipid-based drug delivery systems represent the cutting edge of pharmaceutical innovation in drug delivery. The biocompatibility and ...