These are likely to dominate the future antibody therapeutic market, but many of them express poorly and have aggregation issues leading to delays to projects. Fusion Antibodies utilizes unique ...

Antibodies are among the most important protein ... and identify potential aggregation, which could compromise activity. As recombinant technologies become faster and cheaper, Bradbury reckons ...

Antibody-drug conjugates (ADCs) are a new class of anti-cancer therapeutics that are both novel and highly targeted. Grafting monoclonal antibodies to a cytotoxic payload enables a highly potent ...

However, their manufacturing can also form mis paired products, fragments and high levels of aggregation, resulting in downstream purification polishing challenges for traditional processes that ...

Antibodies, known for their precise target binding, offer a powerful tool for investigating these structures, but generating antibodies against such transitory targets has been a major hurdle.

The toxic aggregates that form in diseases like Parkinson's and Alzheimer's are challenging to study, but a new approach can help and may provide exciting new avenues for drug development This new ...