implying they stimulate nonredundant pathways. In murine models of colon cancer and melanoma, the addition of anti-TNFRSF25 agonist antibody enhanced antitumor responses (Fig. 1). Notably ...

It was initially thought that girolline's possible antitumor effect was due to its being a general translation inhibitor ... The stalled ribosomes are then attacked by the ribosome-associated quality ...

Our laboratory is dedicated to understanding the consequences of activation of these pathways and to using this information to develop mechanism ... inhibition of upstream receptors increases their ...

BioMed X, an independent biomedical research institute based in Heidelberg, Germany, has announced a new collaboration with ...

This approach, which proposes a dual attack against the tumor, has shown promising results in preclinical models, achieving a complete and long-lasting antitumor response in mouse models with ...

Zumutor's pipeline has two more assets targeting NK cell activation pathways involved in antitumor functions. The company was founded in 2016 and has raised a total of 27Mil$ from a strong ...