Stabilizing hydrophobic interactions occur between the side chains of Y204 and P461 with the aryl moiety of 3b. Additionally, the side chain of H263 is positioned such that the Cε2 carbon atom ...
FIGURE 1. Selected examples of naturally occurring 1,3-enynes and synthetic drugs, which incorporate an 1,3-enyne motif. SCHEME 2. Possible products of the ...
Aryl halides are sweet-smelling mixes in which halogen molecules supplant at least ... giving the triangle-like structure of three benzene rings (Figure 4a). A triphenylene moiety is shaped in the ...