For years, breast cancer treatment has been guided by genetic alterations found in tumor tissue, typically through invasive biopsies.

A new study on circulating tumor DNA (ctDNA) testing for advanced breast cancer has unveiled encouraging results, with high ...

More and more studies show that men face risks of cancer from BRCA1 and BRCA2 genetic mutations that are most often associated with breast and ovarian cancers in women. According to a JAMA ...

Pharmacogenomics. 2012;13(13):1523-1535. 5-year survival for stage III and IV (%): carriers, 38.1; noncarriers, 24.5 Median survival: p = 0.002 5-year survival for stage III and IV: p < 0.001 [46 ...

The former NBC news anchor, 49, revealed last month in an Instagram post that she had tested positive for the BRCA1 gene mutation, putting her at a higher risk for breast and ovarian cancer.

Genetics significantly impact cancer risk, particularly in inherited mutations like BRCA1/BRCA2, which increase ...

Sensitivity to ionizing radiation is compelling evidence that BRCA1-and BRCA2-deficient cells are defective in repair of DSBs. As discussed above, 2 separate pathways play major roles in DSB repair in ...

Most studies assessing BPO are retrospective studies and nonrandomized ( Table 1) and have been evaluated in women at risk for carrying BRCA1/2 mutations. A study by Lu et al [42] reviewed the ...

But, new research has discovered a method to isolate those dangerous mutations, thereby finding a way to fix them. When BRCA1 ...

When the gene testing results returned, Mrs Gard was told she tested positive for the BRCA1 gene mutation, a faulty gene that significantly increases the odds of developing ovarian cancer among ...