As a leading authority on DNA repair contests findings that he falsified data about a key breast cancer gene, other researchers in the field are preparing a salvage operation to make sure good science ...
People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of them doesn't function. For cancer-suppressor genes like BRCA1 ...
The double ring, spool-like structure of RAD52 protects replicating DNA in dividing cells. A study led by the University of ...
Scientists at the University of Iowa have made an exciting discovery that could lead to new cancer-fighting drugs. They found ...
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BRCA1 gene mutations may not be key to prostate cancer initiation, as previously thoughtThe limited involvement of BRCA1 suggests that tumors harboring BRCA1 variants may not rely on homologous repair deficiency, potentially limiting their responsiveness to PARP [inhibitor]-based ...
Researchers from the University of Iowa have unveiled the structure of a protein that plays a key role in protecting DNA ...
Mutations in BRCA1 and BRCA2 -- tumor suppressor genes that play a crucial role in DNA repair -- substantially increase the likelihood of cancer.
A real-world study reveals the need for increased homologous repair deficiency and BRCA1/2 testing in patients with ovarian ...
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