These investigators assessed the poorly understood biology and genetics that underlie the transformation of CLL to RS and that impedes progress against this aggressive malignancy. A study of 1230 ...

New data suggest venetoclax may offset the negative prognostic impact of short telomeres in patients with chronic lymphocytic ...

Preclinical research findings from the University of North Carolina Lineberger ... CAR-T cells generated from both healthy ...

The study’s findings are rooted in real-world applications. Researchers recruited 20 CLL patients to participate in structured exercise sessions lasting 20-30 minutes. Each patient engaged in ...

In an interview, Paolo Ghia, MD, PhD, discussed updated data from the phase 2 CAPTIVATE trial of ibrutinib and venetoclax in ...

Genome studies of chronic lymphocytic leukemia (CLL) have revealed the remarkable ... subclonal alterations (data not shown). All these findings suggest that in untreated patients the accumulation ...

UNC Lineberger researchers discovered a three-drug cocktail that enhances the production of T-memory stem cells (TSCMs) in ...

Preclinical research findings from the University of North Carolina Lineberger Comprehensive Cancer Center identified a cocktail of three different drugs that can be used to generate more robust ...

Findings from the survey are the first to report the emotional perspectives of Hispanic, Black, and Asian patients with CLL and their unique experiences and challenges throughout their blood cancer ...

SHM occurs in antigen-activated germinal center B cells and in the setting of CLL, SHM status is used to define distinct ... of the new Oncomine® Leader –J assay and compared our findings to our ...

Findings also show that ethnically diverse patients are underutilizing online support groups, with very few reporting using this resource to learn about CLL (19% Hispanic; 23% Asian; and 35% Black).