Study participants were randomly assigned to receive a single drop in each eye of Brimochol PF, carbachol, or vehicle topical ophthalmic solution at each visit. The primary endpoint was the change ...

Brimochol PF (carbachol/brimonidine tartrate fixed-dose combination) demonstrated improvements in near vision vs. vehicle at all study time points up to 8 hours (P <.008). Additionally ...

In a phase 3 trial, Tenpoint Therapeutics’ eye drop—a combination of carbachol and brimonidine—improved vision for patients with presbyopia for up to eight hours. The top-line results come f ...

“In our studies, brimonidine increased the magnitude and duration of action of carbachol and reduced the incidence of hyperemia (eye redness) over carbachol alone. BRIMOCHOL™ PF is the only presbyopia ...

Newly generated human embryonic stem cell‐derived atrial‐like cardiomyocytes resemble human atrial cardiomyocytes and prove to be a valuable model for pre‐clinical drug screenings to identify ...