Our results highlight several points of physiologic and translational significance. First, the results suggest that the postnatal loss of cardiomyocyte cytokinesis may be a protective effect to ...
One approach involves microfluidic chambers designed for real-time observation of cardiomyocyte contractility and electrophysiological signals. These chambers maintain a controlled environment, ...
These developmental gene expression changes not only affect cardiomyocyte contractility but also their growth and proliferation potential. Furthermore, cardiomyocytes obtained from different species ...
PAH results in altered RV structure and function at different scales from organ-level hemodynamics to tissue-level biomechanical properties, fiber-level architecture, and cardiomyocyte-level ...
Since Dlg5, STRIPAK and the Hippo pathway are conserved a similar mechanism may contribute to muscle or cardiomyocyte growth in humans. Here, we employ a systematic in vivo muscle-specific RNAi screen ...
Cardiomyocyte (CM) maturation in mammals is accompanied by a sharp decline in their proliferative and regenerative potential shortly after birth. In this study, we explored the role of the mechanical ...
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