Deciphering the gut biome's, including helminths', influence on human trained immunity will unlock novel immunotherapies harnessing the immune reprogramming potential of their secreted factors and ...

NK cell-mediated anti-tumor immunity. In mice with MHC class I-negative tumors, adoptively transferred- or Flt3 ligand-expanded DC promoted NK cell-dependent anti-tumor effects. In vitro studies ...

You have full access to this article via your institution. In conclusion, the literature cited above indicates that γδ T cells do function as an integral part of the cell-mediated immune ...

This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

2024. Fasting reshapes tissue-specific niches to improve NK cell-mediated anti-tumor immunity. Immunity. 57(8):1923-1938.e7. Santosa EK, Kim H, Rückert T, Le Luduec JB, Abbasi AJ, Wingert CK, Peters L ...

8 Profiling these patients’ immune cells revealed that the response was partly mediated by an increase in NK cell populations ... Going forward, Delconte’s team hopes to achieve enhanced antitumor ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...

An antibody is a component of humoral immunity. Antibodies can be effective defenders against both bacteria and ... A lipid (fatty) covering that surrounds a viral particle. It is derived from the ...

Finally, CD8 + T cell-mediated antitumor immunity to promote immune escape was suppressed. Wondering whether blockade of the ...

However, especially in “clean” Western societies, the immune system also poses a significant threat to the individual, as immune cell mediated diseases such as autoimmunity and allergy are becoming ...