Collagen, the body's most abundant protein, has long been viewed as a predictable structural component of tissues. However, a ...

The most prevalent protein in the body, collagen, has long been thought to be a predictable structural element of tissues.

Here we use a peptide self-assembly system to design collagenous assemblies based on the C1q collagen-like region. Using cryo-EM we solved a structure of one assembly to 3.5 Å resolution and built an ...

"The absence of the superhelical twist allows for molecular ... X-ray crystallography and fiber diffraction have provided valuable insights but could not capture collagen packing in complex ...