Mutations in the polymerase that replicates mitochondrial DNA, Pol γ, lead to a range of human neuromuscular and ophthalmologic diseases. Loss of function of the TLS polymerase Pol η leads to ...

Acurx Pharmaceuticals, Inc. (NASDAQ: ACXP) ("Acurx" or the "Company"), a late-stage biopharmaceutical company developing a new class of small molecule antibiotics for difficult-to-treat bacterial ...

Acurx Pharmaceuticals’ DNA Polymerase IIIC Inhibitors receives Japanese patent: Staten Island, New York Thursday, February 20, 2025, 18:00 Hrs [IST] Acurx Pharmaceuticals, Inc., ...

Topoisomerase 2β (TOP2B) introduces transient double strand breaks in the DNA helix to remove supercoiling structures and unwind entangled DNA strains. Advances in genomic technologies have enabled ...

Two Indian men made unwanted advances towards two Thai women at Pattaya beach, causing discomfort. One of the men began ...

The process of transcription elongation by RNA polymerase II (Pol II), in which Pol II travels along DNA and synthesizes RNA from DNA, is essential for proper gene expression in all eukaryotic cells.

Our understanding of the DNA damage responses of human cells to radiation has increased remarkably over the recent years although some notable signaling events remain to be discovered. Here we provide ...