In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks ...

In a study published in Nature, researchers led by Prof. TONG Minghan from the Center for Excellence in Molecular Cell Science (Shanghai Institute of ...

Each of the two strands of the DNA molecule acts as a template for the synthesis of a complementary strand. DNA double-strand breaks induce local genome maintenance and inhibition of replication ...

Torsional stress in chromatin plays a fundamental role in cellular functions, influencing key processes such as transcription, replication, and chromatin organization. Transcription and other ...

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...

The CRISPR-Cas9 system offers groundbreaking genome editing capabilities, yet off-target cleavage raises concerns about ...

A study published in Nature Communications and conducted by researchers from the Institute of Physics of the Chinese Academy of Sciences revealed new ...

From understanding hereditary diseases to predicting drug responses, sequencing helps researchers uncover the subtle language ...

Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals. For women, ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

Man paddles 6,000-mile long 'Great Loop' by canoe, passes through Grand Strand Trump says 'dictator' Zelenskyy 'better move fast' on Ukraine This Tiny Caribbean Island Off the Coast of Puerto Rico ...

Department of Respiratory and Critical Care Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, P. R. China Department of Chemistry, State Key ...