The clinical effects of therapeutic interventions and the pathophysiological consequences of demyelination are followed in patients by magnetic resonance imaging (MRI), which reveals cortical ...

An MRI of her brain showed several demyelination plaques, with a particularly large one in the subcortical area of the parietal lobe with clear enhancement by gadolinium (Figure, bottom).

Multiple sclerosis (MS) has long been considered a demyelinating disease, with the accumulation of plaque in the brain and spinal cord appearing to parallel disease progression. More recently ...