Drug developers' dreams of silencing RNA as a way to step in front of a range of diseases have not lived up to early-day hype ...

Feb. 28, 2025 — A study has provided new insights into the role of the brain as a crucial control center and the origin of obesity and type 2 diabetes. The hormone insulin plays a key role in ...

In this study, the authors demonstrated that exosomes can serve as delivery vehicles to introduce AGO2-loaded siRNA into the cytoplasm of bacteria, and in turn down-regulated gene expression of ...

Diabetes is a chronic disease that occurs when ... To this end, small interfering ribonucleic acid (siRNA) knockdown of 16 GPCRs was performed, followed by protein quantification and ...

Junevity Inc. has raised $10 million in seed funding to support its work creating silencing RNA (siRNA) therapeutics to address metabolic and age-related diseases, including type 2 diabetes, obesity ...

Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced presentation of preclinical data supporting the advancement of ...

Gestational diabetes is a common condition in which a person’s blood glucose (sugar) increases during pregnancy. While there are factors that can increase the risk of gestational diabetes—like having ...

In Type 2 diabetes, Junevity’s first siRNA therapeutic candidate improved glucose control and insulin sensitivity in diabetic mice without causing weight gain or other side effects associated ...

Blurry vision can be an early warning sign of diabetes. It's also a sign of advanced diabetic eye disease. If blood sugar goes uncontrolled, diabetes causes progressive damage to structures in the ...

About nine out of ten people with diabetes have type 2 diabetes. The good news is that type 2 diabetes can be prevented or postponed by making healthy lifestyle choices. Diabetes is a lifelong ...

Diabetes describes a group of metabolic diseases characterized by high blood sugar levels. Diabetes can be caused by the pancreas not producing insulin (type 1 diabetes) or by insulin resistance ...