The Substance follows Elisabeth Sparkle (Demi Moore), an aging celebrity who turns to a mysterious miracle drug called The Substance that makes her decades younger. However, Sparkle gets more than ...

After Elisabeth is abruptly fired from her TV job, “Sparkle With Elizabeth,” the gutted actress learns of an underground drug called the Substance that promises to create a younger ...

Demi Moore's full-on nudity movie The Substance has been dubbed the “grossest thing you will see all year” by horrified critics. The 61-year-old is generating Oscar buzz for her role in the ...