Learn about cystic fibrosis, a genetic disorder that affects the lungs, pancreas, and other organs, and how to treat and live with this chronic disease. 12 min read What Is Cystic Fibrosis? Cystic ...

Cystic fibrosis (CF) is a multi-organ disease caused by loss-of-function mutations in CFTR (which encodes the CF transmembrane conductance regulator ion channel). Cystic fibrosis related diabetes ...

A biorepository is a place, similar to a library or bank, where biological samples are stored for use in research. Since 2006, the Cystic Fibrosis Foundation has collected and stored samples from a ...

Sionna Therapeutics is eyeing a $156 million IPO as the cystic-fibrosis-focused biotech looks to take its lead candidate into phase 2. The Waltham, Massachusetts-based company already unveiled ...

TNKS1/2 proteins are key players in the regulation of WNT/β-catenin and Hippo signaling pathways, which are implicated in various diseases, including cancer, immune evasion and fibrosis. Consequently, ...

Angiotensin-converting enzyme (ACE) inhibitors are oral medications that lower blood pressure. They are used to treat a variety of heart-related conditions including high blood pressure, coronary ...

and in air–liquid interface cultures of primary human bronchial epithelial cells harvested from an individual with cystic fibrosis. A plasmid designed to silence epithelial sodium channel (ENaC) ...

inhibitor for the treatment of idiopathic pulmonary fibrosis (IPF). In May 2024, Alentis Therapeutics announced that the US Food and Drug Administration (FDA) had granted lixudebart (ALE.F02 ...

To date, research in basic science has disclosed a range of pathophysiological mechanisms of post-MI cardiac fibrosis, and many attractive inhibitors and antagonists have been developed based on the ...

(MENAFN- GlobeNewsWire - Nasdaq) The pulmonary fibrosis market is driven by the increasing prevalence of pulmonary fibrosis, especially idiopathic pulmonary fibrosis (IPF), among the aging ...