Calcitonin gene-related peptide (CGRP) inhibitors are now considered a first-line treatment used to treat and prevent migraines. There are two types of CGRP medications: monoclonal antibodies and ...
Identification of autoantigens targeted by RA autoantibodies has been of major interest. Alpha-enolase (ENO1) is considered as a pivotal autoantigen in early RA. Whatever the nature of this molecule, ...
Apolipoprotein C3 (apo C3) is primarily secreted by the liver and is involved in promoting sterile inflammation and organ damage under pathological conditions. Previous studies have shown that apo C3 ...
BRAF V600E 突变在结直肠癌(CRC)中是一个重要的生物标志物,约占所有结直肠癌病例的 10%。这一突变通常与肿瘤的侵袭性、预后不良以及对常规化疗的耐药性相关联[1]。研究显示,BRAF V600E 突变导致肿瘤细胞激活 MAPK ...
2 Department of Pathology, Shandong University Medical School, Jinan, China Correspondence to Dr Lin Wang, Key Laboratory for Rare and Uncommon Diseases of Shandong Province, Research Center for ...
These strategies await further research on drugs or targeted inhibitors to make significant advancements towards reducing morbidity, mortality, and improving disease-free survival rates among OSCC ...
Activin induces tissue inhibitor of matrix metalloprotein-1 ... Anticitrullinated α-enolase autoantibodies were identified as a serum biomarker of high specificity in four cohorts with rheumatoid ...
1 Department of Anatomy and Neurobiology, School of Basic Medical Sciences, Central South University, Changsha, China 2 School of Materials Science and Engineering, State Key Laboratory of Powder ...
Aromatase is an enzyme that converts testosterone to estradiol, a type of estrogen. One study found that taking an estrogen blocker called an aromatase inhibitor while on testosterone therapy reduced ...
The respective diagnoses were made on the presence of classical clinical symptoms (gastrinoma: peptic ulceration; insulinoma: hypoglycaemia; carcinoid tumour: severe diarrhoea and/or flush), ...