Alpha-enolase (ENO1) is considered as a pivotal autoantigen in early RA ... More precisely, the effects of ENO1 specifically involved the CD14-dependent TLR4 pathway. Conclusions Together, these ...

Three very important feasts and the pattern of the Tabernacle and the Ark of the Covenant — all symbolic of Christ and His relationship with believers today. And let them make Me a Sanctuary; that I ...

Last year, the CMS Innovation Center launched the Quality Pathway strategic initiative to strengthen the focus on quality in alternative payment models. Since it was created, the CMS Innovation ...

In recognising this UK Sport’s approach to funding reflects that journey and works on the basis of an athlete pathway with three clear and distinct levels that make up the World Class Pathway. The two ...

Sepsis and septic shock remain leading causes of morbidity and mortality for patients in the intensive care unit. During the early phase, immune cells produce various cytokines leading to prompt ...

More than three years after the Pathways Alliance oilsands group first announced plans for a proposed $16.5-billion carbon capture network in northern Alberta, the consortium still hasn’t given ...

BRAF V600E 突变在结直肠癌（CRC）中是一个重要的生物标志物，约占所有结直肠癌病例的 10%。这一突变通常与肿瘤的侵袭性、预后不良以及对常规化疗的耐药性相关联[1]。研究显示，BRAF V600E 突变导致肿瘤细胞激活 MAPK ...

Apolipoprotein C3 (apo C3) is primarily secreted by the liver and is involved in promoting sterile inflammation and organ damage under pathological conditions. Previous studies have shown that apo C3 ...

In cell culture experiments, ACPAs could bind to and modulate a variety of cellular targets, such as macrophages, osteoclasts, synovial fibroblasts, neutrophil granulocytes, mast cells, dendritic ...

2 Department of Pathology, Shandong University Medical School, Jinan, China Correspondence to Dr Lin Wang, Key Laboratory for Rare and Uncommon Diseases of Shandong Province, Research Center for ...