Reactions analogous to flavin oxygenation have been proposed for enzymes catalyzing the cofactor-independent oxygenation of, for example, urate, 3-hydroxy-4-(1H)quinolones, p-hydroquinone ...

The 2009 ESBOC meeting covered advances in synthesis, biosynthesis and biological mechanisms of vitamins and cofactors. Recent exciting developments in the field include the development of 'green ...

This enzyme has a unique metal cluster, termed the FeMo-cofactor, that requires eight electrons and eight protons to reduce N ...

Enzyme catalysis has the capability to make chemical synthesis cleaner, more energy-efficient and generate less waste. However, enzymes do not work in isolation; they often require extremely expensive ...

The researchers used site-specific mutagenesis to gain new insights into how the cofactor precursor is integrated into the enzyme and how individual amino acids are involved in anchoring and ...

The overarching goal of his research is to understand how enzymes control catalysis. The Stull lab primarily focuses on the class of enzymes that use riboflavin-derived cofactors (flavin-dependent ...