The PPAR family and AMPK are key regulators of glycolipid and energy metabolism in DCM and play key roles in mitigating NOX-mediated oxidative stress. In HF, MI, and HCM, NOX4 has been recognized to ...

Bronchopulmonary dysplasia is a prevalent respiratory disorder posing a significant threat to the quality of life in premature infants. Its pathogenesis is intricate, and therapeutic options are ...

Elafibranor is developed by Genfit (GNFT) in collaboration with Ipsen. It is an oral dual PPAR α/δ agonist. Key findings from the phase 3 ELATIVE Trial: Primary Endpoint: 51% of patients ...

The endocrine and sarcoma surgery section at Karolinska treats over a thousand patients with sarcoma and tumors and/or functional disorders in endocrine organs every year, in a multidisciplinary ...