A discovery at Duke-NUS Medical School offers new hope in the battle against pulmonary fibrosis, a debilitating lung ...

The secret to reversing cellular aging may lie hidden in a single protein that can influence a cell's age from young to old.

A protein called Runx2 contributes to the abnormal activity of lung cells that drive pulmonary fibrosis, a new study shows.

Aging reshapes breast tissue, boosting cancer risk via epigenetic and immune shifts. Key insights for clinical practice.

Carcinoma-associated fibroblasts (CAFs) derived either from resident fibroblasts or tumor-infiltrating mesenchymal stem cells (MSCs) are a major component of the stroma in desmoplastic cancers. Recent ...

Pancreatic cancer is fueled by connections to the nervous system. This is reported by scientists from the German Cancer ...

Inguinal hernias affect millions of men, with half of them likely to develop the condition by age 75. These hernias occur ...

In a first, aging-related gene expression changes in breast tissues are linked to alterations in chromatin accessibility.

GRAPHICAL ABSTRACT In this study, we developed an in vitro technique to transdifferentiate human dermal fibroblasts into osteoblast-like cells. Bone marrow-derived mesenchymal stem cells, the true ...

The key to reversing cellular aging may lie in a protein responsible for toggling cells between a "young" and an "old" state.

The spreading and migration ability of NIH3T3 fibroblasts was assessed using a scratch model. The cells were seeded into a 24-well plate at a concentration of 5 × 10 4 cells/well and cultured in ...

Fibroblasts are the most common cell type in connective tissue. They can be compared to 'nature's stitches', holding together damaged tissue until it is healed. Fibroblasts remain sleeping until they ...