A new study has revealed the existence of bifunctional diterpene cyclases/synthases (DCSs) in bacteria, offering compelling evidence that the plant terpene synthase gene family, termed TPS, originated ...

Johns Hopkins University School of Medicine researchers have discovered a dual regulatory mechanism safeguarding ...

Conversely, mitochondrial fusion allows the mixing and exchange ... The authors identified a gene-expression signature associated with immune responses in the brains of mice lacking Parkin and ...

Whole genome sequencing can be an exceptionally valuable tool in cancer diagnostics. The application of this technique can ...

Feb. 20, 2025 — Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

Akribion Therapeutics emerges from stealth with €8 million in seed funding to develop a novel cancer RNA-guided approach ...

The new doors AI and machine learning are opening to scientists undoubtedly will invite weighty ethical and moral questions ...

He has been in minimal residual disease negative remission for 10 months after allo-HSCT. Result: His bone marrow karyotype showed a balanced translocation between chromosomes 8 and 17, leading to a ...

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled “Acquired RUFY1-RET rearrangement as a mechanism of resistance to lorlatinib in a patient with CD74-ROS1 ...