研究结果表明，TGF-β信号阻断是NK细胞有效对抗肝细胞和其他表达高水平TGF-β的恶性肿瘤的必要条件。 这项研究证明了使用 ipsc 来源细胞替代大泡性 ...

帕金森病（Parkinson’s Disease，PD），是一种复杂的神经退行性疾病，也是世界上第二常见的神经退行性疾病，仅次于阿尔茨海默病（AD），影响着约 1?% 的 65 岁及以上老人。随着全球人口老龄化，帕金森病患病率还将大幅增加。 人诱导多能干细胞（hiPSC）来源的中脑多巴胺能细胞（mDAC）为帕金森病的自体细胞疗法提供了一个有前景的来源，但标准化的调控标准对于临床转化至关重要。 20 ...

诱导多能干细胞（iPSC）能再分化成特定的细胞类型、组织和器官，联合基因编辑技术使用，可用于探索疾病发生的机制、开发新型有效的药物和细胞 ...

CD16 iPSC-derived NK (iNK) cell – Fate’s lead iPSC-derived cancer immunotherapy is a targeted iNK cell product created from a master engineered pluripotent cell line that expresses a high ...

We have dedicated cleanrooms for induced pluripotent stem cells (iPSC), mesenchymal stromal cells (MSC), chimeric antigen receptor T-cells (CAR-T), T-cell receptor-engineered T-cells (TCR-T), natural ...

Chen became a graduate student for the Spencer lab in May of 2015. After graduating in , Chen became a post doc for the Spencer Lab. Following the completion of her post-doctoral work, Chen took a ...

The trial, dubbed CARAMEL, will mark the first evaluation of an allogeneic iPSC-derived CD19-directed NK cell therapy in autoimmune disorders. The investigator-initiated trial, sponsored by ...

FATE uses its platform with iPSC technology that can create reprogrammed stem cells. In turn, these specially designed stem cells can produce all kinds of human cells, including T and NK cells.