Although not specifically approved for the treatment of bleeding peptic ulcers, proton pump inhibitors (PPIs ... platelet activity and minimization of fibrinolysis, thereby aiding clot formation ...

TNF-α causes suppression of fibrinolysis by increasing PAI-1 levels ... Increased levels of TAFI are an important mechanism for the inhibition of the fibrinolytic system during sepsis.

In patients eligible for fibrinolytic therapy who also have timely primary PCI available, the 1999 guidelines advised fibrinolysis ... anticoagulants, inhibitors of RAAS and lipid-lowering agents ...