Its pathological features include: A lot of misfolding and abnormal aggregation of amyloid protein (Aβ); Autophagy disorder, oxidative stress, neuroinflammation, abnormal phosphorylated tau protein ...

LKB1 Expression Correlates with Increased Survival in Patients with Advanced Non-Small Cell Lung Cancer Treated with Chemotherapy and Bevacizumab. Tumor BRCA1 Reversion Mutation Arising during ...

该研究揭示了lkb1缺陷肿瘤的关键代谢脆弱性，可用于靶向癌症治疗。 在一项新的研究中，研究人员取得重大突破：他们确定了有史以来第一个与线 ...

Although LKB1 has basal enzymatic activity, its functional strength and regulatory efficiency ... β1 is specifically phosphorylated by the autophagy-initiating kinase ULK1, a feature absent in β2.

State Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, China ...

The alteration frequency including mutations, structural variants, amplifications, deep deletions, and multiple alterations of LKB1 in tumors. Listed in descending prevalence are LKB1 genetic ...

Institute of Digestive Diseases, Longhua Hospital, China-Canada Center of Research for Digestive Diseases (ccCRDD), Shanghai University of Traditional Chinese Medicine, Shanghai 200032, P. R. China ...