CIRBP Family, Tumors, Molecular Mechanisms, RNA-Binding Proteins, Cellular Stress Share and Cite: Cai, Y. , Wang, T. and Zhan ...

retriever generates disease-specific transcriptional drug response signatures by merging transcriptional signatures over time, concentration, and cell-type. These signatures can then be matched to ...

In cancer-associated cachexia, elevated TNF-α and IL-6 exacerbate muscle and fat loss by regulating multiple metabolic signaling pathways, which could be ameliorated by Z526's suppression of NF-κB ...

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Boulevard, Aurora, Colorado 80045, ...

In October 2024, Lutris successfully completed enrollment in the international phase 2 trial of LUT014 in patients with metastatic colorectal cancer (mCRC) treated with EGFRi therapy who develop ...

Ongoing research aims to understand these interactions and improve immunotherapy effectiveness by targeting pathways like adenosine signaling. This would ultimately enhance the body’s natural immune ...

This year’s theme, “Empowering Progress: New Frontiers in Cancer Care Pathways,” highlights some of the latest advancements and collaborative efforts in cancer care within the Cayman Islands.

1Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California.

and fibrosis to promote the development of MASLD via regulation of Hippo-YAP1/TAZ Pathway. MST1/2, 20-like kinase 1/2; LATS1/2, large tumor suppressor 1 and 2; P, phosphorylation; MAP4K, ...

This doesn’t only determine if water is ‘hard’ or ‘soft’: research has linked it to certain health problems, from bone fractures and eczema to stroke, even cancer. A study, published ...

A new map has revealed that up to 25 percent of Americans ... Studies show radon exposure is the second leading cause of lung cancer in the US after smoking, leading to about 21,000 lung cancer ...

being responsible for 220,000 lung cancer deaths worldwide each year, 21,000 of whom are in the U.S. Map from the paper revealing average predicted community-level radon concentrations at ...