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Nat Metabol:重编程免疫细胞的代谢通路或能改善癌症疗法的疗效
在过去几十年里,诸如检查点抑制剂疗法等免疫疗法通过训练机体免疫系统来攻击癌症,彻底改变了癌症的治疗;然而,这些疗法通常在实体瘤治疗中效果不佳,在实体瘤中,敌对的肿瘤微环境(TME)阻碍了免疫细胞的活性,比如,在诸如 胰腺癌 ...
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