The work presents a molecule detection method for single-molecule localization microscopy. By means of probabilistic thresholding with control over false positive detections, the method improves ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. The binary collision of nanoscale droplets is studied with molecular dynamics ...

This study investigates the potential clinical synergy between the PARP inhibitor niraparib (Zejula) and concomitant statins, exploring their combined effects on progression-free survival (PFS) in ...

The authors performed extensive coarse-grained molecular dynamics simulations of 140 different prion-like domain variants to interrogate how specific amino acid substitutions determine the driving ...

These shifts highlight specific molecular mechanisms, such as immune activation and structural integrity decline, across various cell types. These findings could help reveal brain regions and ...

Behind the Paper is a channel for researchers to share the real stories behind the latest research papers, from conception to publication, the highs and the lows. We welcome our authors to share ...

Attempts to design small molecule therapies directed to this cytokine have not led to approved products yet. Here we report the discovery and development of a potent small molecule inhibitor of TNF ...

The measurement isn’t really for a specific atom, but it is an average for a lipid molecule, which is still impressive. You essentially measure the diameter of an oil drop spread over water.