Monocytes are attracted by chemokines and specific receptors to precise areas in vessels or tissues and transdifferentiate into macrophages with tissue damage or infection. Adherent monocytes and ...

zju.edu.cn Objective Macrophages are among the most abundant cells in the colon tumour microenvironment, and there is a close relationship among monocytes, macrophages and the gut microbiota.

These results support the idea that NOX2 signaling in macrophages plays a role in the pathogenesis of obesity-induced metabolic disorders. Potentially, obesity may be reduced by targeted suppression ...

Researchers explore the cellular and molecular adaptations associated with human secondary lymphoid tissue in adults during ...

The monocyte effect. Monocytes/macrophages (promonocytes in the bone marrow, circulating monocytes, tissue macrophages) play a major role in the induction and regulation of immune reactivity.

A recent Brazilian study published in Nature Cardiovascular Research has highlighted promising pathways for preventing and ...

Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...

Objective Liver injury impacts hepatic inflammation in part via Toll-like receptor (TLR) signalling. Triggering receptor expressed on myeloid cells 2 (TREM-2) modulates TLR4-mediated inflammation in ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.

This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

Here, Olari et al show that alpha-synuclein enhances HIV-1 entry and replication in human T cells, macrophages and microglia which may contribute to the development of neurodegenerative disease.

Abstract Research of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia (FM), two acquired chronic illnesses affecting mainly females, has failed to ascertain their frequent ...