In this manuscript, the authors describe a new AlphaFold2 pipeline called PabFold that can represent a useful tool for identifying linear antibody epitopes (B-cell epitopes) for different antigens.

Different types of antibodies are produced by your immune system. These five antibodies help fight disease by detecting viruses, bacteria, and other pathogens (disease-causing microorganisms) and ...

Sjögren’s antibody testing is done using a blood sample. It checks antibody levels, including anti-SS-A (also called anti-Ro) and anti-SS-B (also called anti-La). Anti-SS-A and anti-SS-B are ...

Therefore, an in-depth understanding of structures of enterovirus and mechanisms of antibody neutralization should be useful for future strategies in guiding the design of a rational antiviral agent ...

The mAbs that have been used in the clinic include murine, chimeric, humanized and fully human antibodies. In particular, chimerization consists of the replacement of the mouse constant domains ...

MIT’s new AI model predicts antibody structures with greater accuracy, aiding disease treatment and streamlining drug discovery. With this model, researchers may be able to discover antibody drugs ...

Ltd. (“MediLink”) to use MediLink’s TMALIN ® antibody-drug conjugate (ADC) platform for the development of a novel LRRC15 ADC, ZL-6201, consisting of an antibody discovered by Zai Lab.

Meplazumab, is a humanized immunoglobulin (Ig) G2 monoclonal antibody, consisting of the complementary-determining regions of anti CD147 murine antibody and the human framework region. It is ...

One way the immune system protects the body from germs and other foreign substances is by making large numbers of antibodies. An antibody is a protein that sticks to a specific protein called an ...