An international team led by researchers at the University of Toronto has found a compound in ginger, called furanodienone ...

An international team led by researchers at the University of Toronto has found a compound in ginger, called furanodienone ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high ...

Researchers found that furanodienone (FDN), a compound in ginger, activates pregnane X receptor (PXR) to reduce gut ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high ...

Atomic nuclei exhibit multiple energy scales simultaneously—ranging from hundreds down to fractions of a megaelectronvolt. A new study demonstrates that these drastically different scales can be ...

Work at the University of Florida has led to the identification of nuclear receptor subfamily 1 group D member 1 (Rev-erbA-α) antagonists reported to be useful for the treatment of cancer, sarcopenia ...

此外，此前研究发现缺失 NR2F6 可增强 T 细胞的抗肿瘤反应，尤其是在免疫检查点抑制期间。本研究进一步表明，在 NK 细胞中缺失 NR2F6 对于缺乏有效 T 细胞表位或下调 MHC-I 表达以逃避免疫监视的肿瘤可能具有重要意义，为联合治疗干预提供了潜在途径。然而，NKp46 表达增强在自身免疫性疾病如系统性红斑狼疮（SLE）中的作用仍有待进一步研究，需要深入探讨 NK 细胞上 NKp46 ...

Drones have the potential to enhance nuclear deterrence, but they also introduce significant risks in terms of escalation control and first-strike stability. Drones and other autonomous vehicle ...