How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

DNA 聚合酶在 DNA 复制过程中发挥着关键作用，其主要形成磷酸二酯键，以确保遗传信息的准确传递。同时，这一过程还涉及到多种相关的化学反应和酶的协同作用。 1. 磷酸二酯键的形成机制：DNA 聚合酶通过催化脱氧核苷酸之间的反应，将一个脱氧核苷酸的 5'磷酸基团与另一个脱氧核苷酸的 3'羟基相连，从而形成磷酸二酯键。这是 DNA 链延长的基础。 2. 对 ...

Comparison of that ancient DNA with modern human DNA showed that the two species had interbred and that people today still carry the genetic fingerprint of that intermixing. Since then ...

This valuable study is a detailed investigation of how chromatin structure influences replication origin function in yeast ribosomal DNA, with a focus on the role of the histone deacetylase Sir2 and ...

Such insights will deepen our understanding of DNA replication regulation in the context of disease states associated with ... DNA was eluted off the beads by denaturation at 98°C for 5 minutes, ...

Of course, though, testing a child's parentage based on physical features is far too subjective — that's typically where DNA tests come in. Such tests can offer a far more scientific way of ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

The intricate link between cholesterol metabolism and host immune responses is well recognized, but the specific mechanisms by which cholesterol biosynthesis influences hepatitis B virus (HBV) ...

A 2015 report published by a private genomics testing company found that 2% of 345 hot dogs tested contained traces of human DNA. However, it was unclear whether that report was a peer-reviewed ...

They also help ensure the accurate copying of DNA during cell replication. This DNA is grouped into segments called genes. Your genes determine your traits, which can range from the smallest ...