To this end, recent clinical and preclinical studies have implicated the epidermal growth factor receptor signaling pathway in chronic pain states. EGFR is one of four members of the ErbB family of ...

Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan Division of Molecular Neuroimmunology, Medical Institute of Bioregulation ...

Our editors also may be in touch with follow-up questions. Cannabidiol (CBD) may offer numerous health benefits, including pain reduction and anxiety relief, without the intoxicatingly ...

We and others have also reported that acute alcohol consumption produces analgesic effects, while chronic alcohol consumption results in hyperalgesia and chronic ... (IPA), to identify the key ...

Pain under the left armpit may result from muscle damage or swollen lymph nodes due to an infection. However, it can also indicate a more serious problem, such as cancer or angina. The armpit is a ...

Darapladib and antioxidants could effectively alleviate the stress-induced hyperalgesia by inhibiting LPC16:0 ... The central mechanism of RISS pain should be further investigated, including the ...

Their plasticity may hold the key to underlying mechanisms in IBS. Our aim was therefore to determine the contribution of each afferent class in each pathway towards post-inflammatory visceral ...

Ear pain has numerous causes. Most are treatable, though some are serious. Conditions responsible for ear pain can strike anyone at any age. If you begin to develop ear pain, it's essential to see a ...

While chest discomfort, such as stabbing pain that comes and goes, can indicate a heart problem, it can also occur due to heart burn and muscle strain. Certain factors can help determine the cause ...

Digital technologies and AI are disrupting the way people live, work, and learn. At the same time, education systems need to become both a rapid producer and an avid consumer of digital and data ...

MANILA, Philippines — A bill to allow graduating junior high school students to pick alternative education pathways has been approved on third and final reading by the House of Representatives ...

Anxiety can sometimes cause physical symptoms like chest pain and pressure. But because these symptoms can also indicate heart conditions, it’s important to get an accurate diagnosis.