Methods We applied empagliflozin treatment to lupus-prone MRL/lpr mice to explore the renal protective potential of SGLT2 inhibitors. An SGLT2 knockout monoclonal podocyte cell line was generated ...

We recommend using your OS's package manager directly instead for improved security but the install script is by no means insecure. In addition to being a runnable CLI tool, D2 can also be used to ...

Diagram of curcumin suppressing intracellular ROS and RIPK3 expression in high glucose ... Curcumin administration protects against podocyte injury by inhibiting ROS generation and downregulating ...

Unique cell junctions, known as slit diaphragms, which feature nephrin and Neph family proteins in addition to components of adherens, tight, and gap junctions, connect adjacent podocyte foot ...