4 University of Giessen and Marburg Lung Center (UGMLC), member of the German Center of Lung Research (DZL), Giessen, Germany Until recently, three classes of medical therapy were available for the ...

Patients with chronic pulmonary obstruction, chronic pulmonary thromboembolism and pulmonary hypertension associated with left heart disease were excluded ... None of the patients had been treated ...

Chronic thromboembolic pulmonary hypertension occurs in a proportion of patients with prior acute pulmonary embolism and is characterised by breathlessness, persistently raised pulmonary pressures and ...

Recommended treatments for PAH-CTD include prostanoids, phosphodiesterase type 5 (PDE5 ... In PATENT-2, clinical worsening (hospitalisation, decrease in 6MWD or persistent worsening of WHO FC due to ...

This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading ... Researchers Identify Over 2,000 Genetic Signals Linked to Blood ...

All patients were prescribed oral PAH specific agents finally, but no one needed parenteral prostanoids. Two patients (15% ... Immunosupressive therapy in lupus-and mixed connective tissue ...

ET indicates endothelin; ETA, endothelin type A; IP, prostaglandin I2; NO, nitric oxide; PAH, pulmonary arterial hypertension; PDE-5, phosphodiesterase type 5; and sGC, soluble guanylate cyclase.

Dietary impact on pulmonary pressures is still poorly understood, but it seems that micronutrient deficiency could be a rare cause of pulmonary hypertension. Relatively frequent in developing ...

Recently, the accumulation of SCs has been implicated in the pathogenesis of pulmonary arterial hypertension (PAH), a progressive condition affecting the pre-capillary pulmonary arterial bed. PAH is ...

The seemingly ordinary news of wedding plans for a young man whom she knew as a child reminds this doctor of how far medicine has come in treating cystic fibrosis — it only took a village.

The 2023 European Society of Hypertension (ESH) and 2017 American College of Cardiology/American Heart Association (ACC/AHA) hypertension guidelines both emphasize proper blood pressure (BP) ...