Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...
To examine potentially pathogenic UTR mutations and their links to RNA stability, we developed a massively parallel reporter assay in which human 5’/3’ UTRs with disease-relevant mutations were ...
Featured pricing is subject to change. We know the feeling — the feeling of waltzing down a supermarket aisle to find the best protein bars, but getting too overwhelmed that we just put our ...
Proteinuria is the presence of too much protein in the urine. It is typically a sign of kidney disease, often in people diagnosed with diabetes, but also can occur with pregnancy, lupus, and other ...
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Years later, it was replaced with exciting-looking “low carb” claims. These days, “high in protein” is a benefit you’ll see touted on lots of products, whether they’re protein powder, bone broth, ...
After a few weeks of forcing herself to eat chicken breast and cottage cheese late in the evening despite not being the least bit hungry, Michelle Wilkes, 59, realized that counting protein grams ...
Mechanistically, HDAC6 deacetylates tripartite motif protein 56 (TRIM56) at K110 in mice, thereby impairing the monoubiquitination cGAS and its DNA binding ability. Overexpression of TRIM56 K110Q ...
Share on Pinterest How much protein you need to build muscle can depend on your weight, activity level, and age. Eating too much may have some risks. Getty Images/Alexander Spatari Protein is ...