Human basophils, first identified over 140 years ago, account for just 0.5-1% of circulating leukocytes. While this scarcity long hampered basophil studies, innovations during the past 30 years, ...

Table 1 Antibody-mediated and genetic depletion models for the in vivo study of basophils in different pathological conditions. The authors also evaluated the cytokines produced in the heart 3 days ...

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C. Ohnmacht et al., “Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths,” Immunity, 33:364-74, 2010. Free F1000 Evaluation Basophils were deemed critical in ...