Ngo et. al use several computational methods to determine and characterize structures defining the three major states sampled by the human voltage-gated potassium channel hERG: the open, closed, and ...

Shaanxi Key Laboratory of Comprehensive Utilization of Tailings Resources, Shaanxi Engineering Research Center for Mineral Resources Clean and Efficient Conversion and New Materials, College of ...

Expert Rev Clin Pharmacol. 2010;3(3):321-329. Despite a propensity to block hERG channel function, as determined by electrophysiology, for a limited number of compounds no cardiac arrhythmias have ...