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上海药物所合作研究药物缓控释放“3D通道迷宫”新机制
“3D通道迷宫”机制为阐明茶碱微丸缓释片的缓控释放机制提供了一个新视角。与传统缓释给药系统的扩散机制不同,“3D通道迷宫”模型强调的是药片内部孔隙网络的门控作用。药物在孔隙网络中自由溶解和扩散,但由于药物还受到曲折复杂的通道网络的限制,不能被视为释放 ...
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